![]() ![]() ![]() Microneedles made up of micro-sized needles of 300 to 800 micrometers (㎛) long have been investigated as a drug delivery system that delivers active ingredients through microchannels. Silk fibroin protein, which displays excellent mechanical strength, was added to the tip of the microneedle to facilitate and accelerate its penetration to the surface of the myocardial tissue in the animal model. The research team constructed a microneedle, a patch-type injection that is attached to the heart tissue to effectively deliver the biofunctional peptide to the damaged myocardial tissue. Growth factors are proteins involved in cell growth and differentiation, and extracellular matrix refers to the rest of the tissue excluding the cells. ![]() Eun Young Jeon (currently at Columbia University) of the Department of Chemical Engineering at POSTECH has developed new mussel adhesive proteins (MAPs) that incorporate biofunctional peptides derived from growth factors or extracellular matrix in the body. A POSTECH research team has developed a treatment for myocardial infarction using a MAP-based microneedle bandage that are attachable to the heart tissue.Ī research team led by Professor Hyung Joon Cha and Ph.D. Recently, new doors have opened to relieve patients of these burdens. Patients not only have to fight their diseases but also must deal with the pain – the more severe the condition, the more painful the injections. ![]()
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